The Streptomyces aureofaciens homologue of the whiG gene encoding a putative sigma factor essential for sporulation

Gene. 1994 May 27;143(1):101-3. doi: 10.1016/0378-1119(94)90612-2.

Abstract

A putative sigma factor-encoding gene, rpoZ, was cloned from Streptomyces aureofaciens. Its deduced protein product showed high similarity to the putative sigma factor encoded by the Streptomyces coelicolor whiG gene. Disruption of rpoZ blocked differentiation at a stage between the formation of aerial mycelium and the development of mature spores.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Bacterial Proteins / chemistry
  • Bacterial Proteins / genetics*
  • Base Sequence
  • Cell Differentiation
  • Cloning, Molecular
  • DNA, Bacterial / genetics
  • DNA-Binding Proteins*
  • Genes, Bacterial / genetics*
  • Molecular Sequence Data
  • Mutagenesis, Insertional
  • Open Reading Frames
  • Sequence Alignment
  • Sequence Homology, Amino Acid
  • Sequence Homology, Nucleic Acid
  • Sigma Factor / chemistry*
  • Sigma Factor / genetics*
  • Spores, Bacterial / growth & development*
  • Streptomyces / genetics
  • Streptomyces aureofaciens / genetics*

Substances

  • Bacterial Proteins
  • DNA, Bacterial
  • DNA-Binding Proteins
  • RpoZ protein, Streptomyces aureofaciens
  • Sigma Factor

Associated data

  • GENBANK/M90414