Health and risk factor surveillance is a critical aspect of an effective ergonomics process. Physical therapists are becoming increasingly involved in many components of the ergonomics process, including health and risk factor surveillance. The purpose of this study was to develop and implement a multistaged active surveillance program for the management and control of cumulative trauma disorders. The surveillance program was established at three newspaper companies consisting of 1,150 employees. This study focused on the first three stages of the multistage surveillance model, which incorporates the use of symptom and job factor questionnaires, specific anatomical surveys, and clinical detection tests. The results of the study indicated that 1) musculoskeletal symptoms in the back, neck, and hands accounted for the majority of reported missed work among the newspaper workers; 2) production workers had a higher prevalence of musculoskeletal symptoms than office workers; and 3) the prevalence of probable carpal tunnel syndrome among the newspaper workers was 1.5%.