Post-prandial Lp(a): identification of a triglyceride-rich particle containing apo E

Chem Phys Lipids. 1994 Jan:67-68:193-8. doi: 10.1016/0009-3084(94)90138-4.

Abstract

A VLDL-like particle containing the apo B100-apo(a) complex was isolated from the post-prandial plasma of subjects fed a fat meal enriched in saturated fatty acids. The abundance of this lipoprotein particle, that we call TG-Lp(a), varied among subjects but not in the same subject. TG-Lp(a), but not the classic Lp(a), contained apo E; this apolipoprotein may cause divergence in cellular uptake and degradation between these two classes of lipoproteins.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Apolipoprotein B-100
  • Apolipoproteins B / metabolism
  • Apolipoproteins E / metabolism*
  • Dietary Fats / administration & dosage
  • Eating
  • Fatty Acids / administration & dosage
  • Humans
  • Hypolipoproteinemias / blood
  • Lipoprotein(a) / blood*
  • Lipoprotein(a) / chemistry
  • Lipoproteins, HDL / blood
  • Lipoproteins, HDL / deficiency
  • Lipoproteins, VLDL / blood
  • Male
  • Triglycerides / blood*

Substances

  • Apolipoprotein B-100
  • Apolipoproteins B
  • Apolipoproteins E
  • Dietary Fats
  • Fatty Acids
  • Lipoprotein(a)
  • Lipoproteins, HDL
  • Lipoproteins, VLDL
  • Triglycerides