No relation between risk of schizophrenia and prenatal exposure to influenza in Holland

Am J Psychiatry. 1994 Jun;151(6):922-4. doi: 10.1176/ajp.151.6.922.

Abstract

The authors compared the risk of schizophrenia in Dutch birth cohorts that were or were not exposed during the second trimester of gestation to the 1957 A2 influenza epidemic. Exposed birth cohorts did not have a higher risk of schizophrenia. These findings suggest that, in some populations, there is no relation between prenatal exposure to influenza and risk of schizophrenia.

MeSH terms

  • Adult
  • Cohort Studies
  • Disease Outbreaks* / statistics & numerical data
  • Female
  • Humans
  • Influenza, Human / epidemiology*
  • Influenza, Human / etiology
  • Male
  • Netherlands / epidemiology
  • Pregnancy
  • Pregnancy Trimester, Second
  • Prenatal Exposure Delayed Effects*
  • Prevalence
  • Registries
  • Reproducibility of Results
  • Risk Factors
  • Schizophrenia / epidemiology*
  • Schizophrenia / etiology
  • Seasons