Abstract
Two related antibiotics, 167-A and 167-B, were isolated from the fermentation broth of a mutant of an inactive wild strain of Amycolata autotrophica. Antibiotic 167-B was found to be cervinomycin A2; antibiotic 167-A is a new representative of the same group and has the structure of 18-O-demethyl cervinomycin A2.
MeSH terms
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Actinomycetales / classification
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Actinomycetales / metabolism*
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Anthracyclines*
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Anti-Bacterial Agents* / chemistry
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Anti-Bacterial Agents* / classification
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Anti-Bacterial Agents* / isolation & purification
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Anti-Bacterial Agents* / pharmacology
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Antibiotics, Antineoplastic* / biosynthesis
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Antibiotics, Antineoplastic* / chemistry
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Antibiotics, Antineoplastic* / isolation & purification
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Antibiotics, Antineoplastic* / pharmacology
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Fermentation
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Gram-Positive Bacteria / drug effects
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Magnetic Resonance Spectroscopy
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Microbial Sensitivity Tests
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Mutagenesis
Substances
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18-O-demethylcervinomycin A2
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Anthracyclines
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Anti-Bacterial Agents
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Antibiotics, Antineoplastic
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cervinomycin A2