Abstract
Three new steroid sulfates 2-4 related to halistanol sulfate [1] were isolated along with the known halistanol sulfate C [5] from the marine sponge Pseudoaxinissa digitata. Halistanol sulfates F [2] and G [3] proved to be cytoprotective against HIV.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antiviral Agents / isolation & purification*
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Antiviral Agents / pharmacology
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HIV-1 / drug effects*
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HIV-2 / drug effects*
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Humans
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Isomerism
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Magnetic Resonance Spectroscopy
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Porifera / chemistry*
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Sterols / isolation & purification*
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Sterols / pharmacology
Substances
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Antiviral Agents
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Sterols
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halistanol trisulfate