In situ localization of HLA class I mRNA in human testis

M Janitz; D Fiszer; J Jaruzelska; A K Simon; A Biro; J A Sachs; M Kurpisz

In situ localization of HLA class I mRNA in human testis

Exp Clin Immunogenet. 1993;10(4):202-7.

Authors

M Janitz¹, D Fiszer, J Jaruzelska, A K Simon, A Biro, J A Sachs, M Kurpisz

Affiliation

¹ Institute of Human Genetics, Polish Academy of Sciences, Poznan.

PMID: 8136177

Abstract

We have used a 0.35-kilobase (kb) antisense RNA probe complementary to the monomorphic regions of both classical and nonclassical HLA class I sequences to detect histocompatibility-class-I-antigen-specific mRNA in human testicular tissue. The message has been clearly detected in the interstitium while less intensive staining was revealed in the peribasal compartment of the seminiferous epithelium.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antisense Elements (Genetics)
Gene Expression
Histocompatibility Antigens Class I / genetics*
Humans
In Situ Hybridization
Male
RNA, Antisense / genetics
RNA, Messenger / genetics*
RNA, Messenger / metabolism*
Testis / immunology*
Tissue Distribution

Substances

Antisense Elements (Genetics)
Histocompatibility Antigens Class I
RNA, Antisense
RNA, Messenger