Antimeasles antibodies in children submitted to different vaccination schedules

Rev Soc Bras Med Trop. 1993 Apr-Jun;26(2):77-82. doi: 10.1590/s0037-86821993000200002.

Abstract

In order to study the measles antibody behavior of three vaccination schedules, 684 children were divided into 4 Groups: Group A (341 vaccinated children under the age of one); Group B (101 children at the age of one); Group C (74 children under the age of one and one at the age of one); Group D (163 unvaccinated children with a history of measles in the past-Group control). Children of Group A presented lower rates and 25.9% of the age group under two did not show any measles antibodies. In Group B, all the children presented antibodies. In Group C only 4.0% did not. In all age groups, the geometric mean HI antibody titers of Group A were lower than the values found in the other groups. The age at vaccination was the factor of greater influence on the results of this study.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aging / immunology
  • Antibodies, Viral / blood*
  • Brazil
  • Chi-Square Distribution
  • Child, Preschool
  • Dose-Response Relationship, Immunologic
  • Hemagglutination Inhibition Tests / statistics & numerical data
  • Humans
  • Immunization Schedule*
  • Infant
  • Measles Vaccine / immunology*
  • Measles virus / immunology*
  • Neutralization Tests / statistics & numerical data

Substances

  • Antibodies, Viral
  • Measles Vaccine