We report a new case of persistent sciatic artery. An 18-year-old girl was hospitalized with ischemia of the left foot. An arteriogram demonstrated a sciatic artery completely persistent. The superficial femoral artery was hypoplasic. A left femoro-popliteal by pass with saphenous vein graft was practised. After the operation, the patient did well and had no complications. We present this observation with a literature review about clinical arteriographic and surgical aspects of this vascular structure and its complications.