A comparative study of evaluating renal scars by 99mTc-DMSA planar and SPECT renal scans, intravenous urography, and ultrasonography

Ann Nucl Med. 1994 May;8(2):147-52. doi: 10.1007/BF03165020.

Abstract

The purpose of this prospective study is to compare 3 types of 99mTc-DMSA renal scan [(a) planar, (b) x-ray type film static SPECT presentation (SPECT-1) and (c) dynamic three-view display of SPECT slices (SPECT-2)], intravenous urography, and ultrasonography in the diagnosis of renal scars. All these studies were performed in 130 pediatric patients, with urinary tract infection (42 patients), vesicoureteral reflux (37), and unilateral or bilateral small kidney(s) (51). The number of renal scars detected was highest with the 99mTc-DMSA renal SPECT-1 scan and next came the 99mTc-DMSA renal SPECT-2 studies. There is a significant difference (p < 0.05) between the ability of planar and SPECT-1 to recognize renal defects. However, SPECT-2 may provide the best stereotactic localization and image quality of all the methods.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child, Preschool
  • Diagnostic Imaging*
  • Female
  • Humans
  • Kidney / pathology*
  • Male
  • Organotechnetium Compounds*
  • Prospective Studies
  • Sensitivity and Specificity
  • Succimer*
  • Technetium Tc 99m Dimercaptosuccinic Acid
  • Tomography, Emission-Computed, Single-Photon*
  • Urinary Tract Infections / diagnosis*
  • Urinary Tract Infections / epidemiology
  • Vesico-Ureteral Reflux / diagnosis*
  • Vesico-Ureteral Reflux / epidemiology

Substances

  • Organotechnetium Compounds
  • Technetium Tc 99m Dimercaptosuccinic Acid
  • Succimer