Abstract
This paper presents the nucleotide sequence of a cDNA encoding a full-length precursor of a novel platelet aggregation inhibitor named trimucrin and a hemorrhagic metalloproteinase from Trimeresurus mucrosquamatus snake venom. The deduced structure of the precursor protein is compared with those of other members of the metalloproteinase/disintegrin family.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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Crotalid Venoms / genetics*
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DNA, Complementary
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Enzyme Precursors / genetics*
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Metalloendopeptidases / genetics*
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Molecular Sequence Data
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Peptides / genetics*
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Platelet Aggregation Inhibitors*
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Sequence Homology, Amino Acid
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Trimeresurus / genetics*
Substances
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Crotalid Venoms
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DNA, Complementary
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Enzyme Precursors
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Peptides
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Platelet Aggregation Inhibitors
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Trimeresurus venoms
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trimucrin
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Metalloendopeptidases