Characteristics of transient otoacoustic emissions in patients with sudden idiopathic hearing loss

Br J Audiol. 1993 Dec;27(6):379-85. doi: 10.3109/03005369309076714.

Abstract

In a prospective study of 24 patients hospitalized with sudden idiopathic hearing loss syndrome (SIHLS), tonal audiometry was conducted first at an early stage after onset (Day O), again a second time (Day A, mean = 4.12 days), and again a third time (Day B, mean = 8.71 days). Transient evoked otoacoustic emissions (TEOAE) were recorded on Days O and A elicited by click stimulation. The question under investigation was whether TEOAE presence, TEOAE amplitude or peak amplitudes for the various 200-Hz-wide bands on Day O could be exploited to assess cochlear function, as indicated by pure-tone audiometry on Days A and B. The TEOAE amplitude on Day O was found to be correlated with improvement in tone threshold on Day B at 2 kHz. One significant correlation emerged between the band amplitude on Day O and the audiometric frequency improvement: on Day B between peak amplitude at 1.2 kHz and 1 kHz frequency improvement. From these results, TEOAE could theoretically be a means to assess cochlear functioning during SIHLS for 1 and 2 kHz frequencies. However, correlations are too weak to form the basis of any predictive test that could be clinically useful.

MeSH terms

  • Acute Disease
  • Adolescent
  • Adult
  • Aftercare
  • Aged
  • Audiometry, Pure-Tone / methods
  • Cochlea / physiopathology
  • Drug Therapy, Combination
  • Female
  • Hearing Disorders / diagnosis*
  • Hearing Disorders / drug therapy
  • Hearing Disorders / epidemiology
  • Hearing Disorders / etiology
  • Hearing Disorders / physiopathology*
  • Humans
  • Male
  • Methylprednisolone / therapeutic use
  • Middle Aged
  • Otoacoustic Emissions, Spontaneous / physiology*
  • Piribedil / therapeutic use
  • Predictive Value of Tests
  • Prognosis
  • Prospective Studies
  • Regression Analysis
  • Syndrome
  • Time Factors

Substances

  • Piribedil
  • Methylprednisolone