Sequence and expression of a monkey testicular transcript encoding tMDC I, a novel member of the metalloproteinase-like, disintegrin-like, cysteine-rich (MDC) protein family

Biochim Biophys Acta. 1994 Aug 2;1218(3):429-31. doi: 10.1016/0167-4781(94)90198-8.

Abstract

Full-length clones encoding a novel member of the metalloproteinase-like, disintegrin-like, cysteine-rich (MDC) family of proteins have been isolated from a monkey (Macaca fascicularis) testicular cDNA library. The encoded putative 82 kDa transmembrane protein (tMDC I) shows striking sequence similarity to other members of the MDC family including rat and monkey EAP I, guinea-pig PH-30 and human MDC protein, as well as a number of snake venom components.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Disintegrins
  • Gene Expression*
  • Gene Library
  • Guinea Pigs
  • Humans
  • Macaca fascicularis / genetics*
  • Male
  • Membrane Proteins
  • Metalloendopeptidases / genetics
  • Molecular Sequence Data
  • Peptides / genetics*
  • Protein Biosynthesis
  • Protein Sorting Signals / biosynthesis
  • Protein Sorting Signals / genetics
  • Proteins / genetics*
  • Rats
  • Sequence Homology, Amino Acid
  • Testis / metabolism*
  • Transcription, Genetic

Substances

  • Disintegrins
  • Membrane Proteins
  • Peptides
  • Protein Sorting Signals
  • Proteins
  • tMDC I protein, Macaca fascicularis
  • Metalloendopeptidases

Associated data

  • GENBANK/X64227
  • GENBANK/X76637