Observation of Cunkou pulse picture, main wave of sphymogram (MW) and foreman rheohemogram and blood pressure (BP) were made on 41 acute stroke patients divide into two groups according to Syndrome Differentiation of TCM; including those involved in viscera and in meridian. The difference between these two groups were significant. The MW, the forearm blood volume (FBV) and BP were all significantly higher in those involved in viscera than that of in meridian. In the different phases of disease course, the MW, FBV and BP changed gradually. During recovery, the MW, FBV and BP were lowered gradually, and finally it remained stable.