Among the various necrotic-ulcerous processes that may become established in the genitalia, one peculiar form of scrotal gangrene was described in 1973 by Piñol et al. under the name of juvenile gangrenous vasculitis of the scrotum. The clinical and pathological features of this entity, of undetermined etiology, allows it to be singled out and differentiated from other pictures of genital ulceration. With the contribution of two new cases, which we have had the opportunity to see recently, we want to call attention towards this distinctive though uncommonly diagnosed entity. Also, to emphasize the good response of the process to appropriate antibiotic and topical treatment in a picture which, due to its initial evolutive nature, to our judgement deserves to be considered within the acute symptomatic complex of the scrotum.