[Is the expression of TNF-alpha and cell adhesion molecules a marker of development of rheumatoid vasculitis?]

Rev Med Interne. 1993;14(10):1018. doi: 10.1016/s0248-8663(05)80135-3.
[Article in French]

Abstract

TNF-alpha, ICAM1, VCAM1, ELAM, CD44 and DR expression were studied (indirect immunoperoxydase methods) on labial salivary gland sections in 5 patients with proven rheumatoid vasculitis (before and after treatment), 5 patients with RA and 5 normal controls. TNF-alpha and cell adhesion molecules were particularly expressed in vasculitic areas of patients with systemic vasculitis and only before the onset of the treatment.

MeSH terms

  • Biomarkers
  • Cell Adhesion Molecules / analysis*
  • Humans
  • IgA Vasculitis / pathology
  • IgA Vasculitis / physiopathology*
  • Salivary Glands, Minor / chemistry
  • Salivary Glands, Minor / pathology
  • Tumor Necrosis Factor-alpha / analysis*

Substances

  • Biomarkers
  • Cell Adhesion Molecules
  • Tumor Necrosis Factor-alpha