[The antiviral properties of 4-iodoantipyrine in an experimental enterovirus infection]

Vopr Virusol. 1994 Jul-Aug;39(4):184-7.
[Article in Russian]

Abstract

The studies of the therapeutic and prophylactic action of a compound from the group of nonsteroid antiinflammatory substances, iodantipyrine-4, in newborn white mice infected with Coxsackie B3 virus showed the drug to possess both therapeutic and prophylactic activity in the acute period of infection.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
  • Antipyrine / analogs & derivatives*
  • Antipyrine / therapeutic use
  • Antiviral Agents / therapeutic use*
  • Coxsackievirus Infections / drug therapy*
  • Coxsackievirus Infections / microbiology
  • Coxsackievirus Infections / mortality
  • Coxsackievirus Infections / pathology
  • Disease Models, Animal
  • Drug Evaluation, Preclinical
  • Enterovirus B, Human* / isolation & purification
  • Mice
  • Myocardium / pathology
  • Pancreas / pathology
  • Time Factors

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Antiviral Agents
  • Antipyrine
  • iodoantipyrine