Tyrosine-hydroxylase immunoreactive fibres in the rat anterior pituitary

Neuroreport. 1994 Jul 21;5(12):1505-8. doi: 10.1097/00001756-199407000-00024.

Abstract

Tyrosine-hydroxylase (TH)-like immunoreactivity was investigated in normal and oestrogenized rat anterior pituitaries in the light of recent studies showing a TH enzymatic activity in the gland and the presence of TH mRNA in endocrine cells. Sparse TH positive fibres, probably dopaminergic as assessed by the absence of dopamine-beta-hydroxylase (DBH) immunoreactivity, were detected in the anterior pituitary, but the detection of TH immunoreactivity in cells was unsuccessful.

MeSH terms

  • Animals
  • Dopamine beta-Hydroxylase / analysis
  • Estradiol / pharmacology*
  • Female
  • Gene Expression / drug effects
  • Immunohistochemistry
  • Nerve Fibers / drug effects
  • Nerve Fibers / enzymology*
  • Pituitary Gland, Anterior / cytology
  • Pituitary Gland, Anterior / drug effects
  • Pituitary Gland, Anterior / enzymology*
  • Polymerase Chain Reaction
  • RNA, Messenger / analysis
  • RNA, Messenger / biosynthesis
  • Rats
  • Rats, Wistar
  • Reference Values
  • Tyrosine 3-Monooxygenase / analysis
  • Tyrosine 3-Monooxygenase / biosynthesis*

Substances

  • RNA, Messenger
  • Estradiol
  • Tyrosine 3-Monooxygenase
  • Dopamine beta-Hydroxylase