Abstract
Three children of MEN IIa-families underwent a prophylactic total thyroidectomy (at the age of 4, 7 and 8 years). Pathologic examination showed a bilateral C-cell-hyperplasia in each case. The annual follow-up of the physically and mentally well-developing children so far showed normal calcitonin provocative testing. Members of risk families should undergo a screening program as early as possible.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Carcinoma, Medullary / genetics*
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Carcinoma, Medullary / pathology
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Carcinoma, Medullary / prevention & control
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Child
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Child, Preschool
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Humans
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Hyperplasia
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Male
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Multiple Endocrine Neoplasia / genetics*
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Multiple Endocrine Neoplasia / pathology
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Multiple Endocrine Neoplasia / prevention & control
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Precancerous Conditions / genetics
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Precancerous Conditions / pathology
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Precancerous Conditions / prevention & control
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Thyroid Gland / pathology
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Thyroid Neoplasms / genetics*
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Thyroid Neoplasms / pathology
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Thyroid Neoplasms / prevention & control
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Thyroidectomy*