Synthetic biological response modifiers. Part II. Synthesis and immunomodulatory properties of some: N2-[omega-(pyrimidin-1-yl)carboxyalkyl]-L-arginines

R Stradi; E Pini; E Rossi; P Cornaglia Ferraris

Synthetic biological response modifiers. Part II. Synthesis and immunomodulatory properties of some: N2-[omega-(pyrimidin-1-yl)carboxyalkyl]-L-arginines

Farmaco. 1994 Dec;49(12):799-804.

Authors

R Stradi¹, E Pini, E Rossi, P Cornaglia Ferraris

Affiliation

¹ Istituto di Chimica Organica, Facoltà di Farmacia, Università degli Studi di Milano, Italy.

PMID: 7893336

Abstract

The synthesis and chemical and physical properties of some N2-[omega-(pyrimidin-1-yl)carboxyalkyl]-L-arginines are here described. Experiments of immunopharmacological evaluations are also described.

MeSH terms

Adjuvants, Immunologic / chemical synthesis
Adjuvants, Immunologic / chemistry
Adjuvants, Immunologic / pharmacology
Animals
Arginine / analogs & derivatives*
Cells, Cultured
Female
Humans
Immunologic Factors / chemical synthesis*
Immunologic Factors / chemistry
Immunologic Factors / pharmacology
Interleukin-6 / metabolism
Mice
Placenta / drug effects
Structure-Activity Relationship
Uracil / analogs & derivatives

Substances

Adjuvants, Immunologic
Immunologic Factors
Interleukin-6
Uracil
Arginine