Molecular cloning of a human complementary DNA encoding an initiation factor 2-associated protein (p67)

Biochim Biophys Acta. 1995 Feb 21;1260(3):333-6. doi: 10.1016/0167-4781(94)00227-t.

Abstract

Rat p67 is an initiation factor-2 associated protein, which plays important roles in translational regulation. A cDNA that encodes a homologue of rat p67 was isolated from a human liver cDNA library. The encoded protein contains 478 amino acids with a calculated molecular mass of 52,891 and an isoelectric point of 5.64. The amino acid sequence is 92% identical to that of rat p67. The corresponding mRNA has a size of approximately 2.1 kb and is present in all tested human tissues.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Aminopeptidases*
  • Animals
  • Base Sequence
  • Cloning, Molecular
  • DNA, Complementary
  • Glycoproteins / chemistry
  • Glycoproteins / genetics*
  • Humans
  • Methionyl Aminopeptidases
  • Molecular Sequence Data
  • Rats
  • Sequence Homology, Amino Acid

Substances

  • DNA, Complementary
  • Glycoproteins
  • Aminopeptidases
  • METAP2 protein, human
  • Metap2 protein, rat
  • Methionyl Aminopeptidases

Associated data

  • GENBANK/U13261