[Holt-Oram syndrome. Review and report of 2 familial cases]

M Oliveira; A Agapito; L Rosário; A Galrinho; N da Silva; A Prates; A M Antunes

[Holt-Oram syndrome. Review and report of 2 familial cases]

Rev Port Cardiol. 1994 Dec;13(12):929-32, 893.

[Article in Portuguese]

Authors

M Oliveira¹, A Agapito, L Rosário, A Galrinho, N da Silva, A Prates, A M Antunes

Affiliation

¹ Serviço de Cardiologia, Hospital de Santa Marta, Lisboa.

PMID: 7873223

Abstract

In 1960 Holt and Oram reported a family in which upper extremity malformations were associated with a secundum atrial septal defect. Since then, more than 200 cases have been reported with a wide spectrum of phenotypes. The authors present the cases of one mother and daughter with Holt-Oram Syndrome (SHO).

Publication types

Case Reports
English Abstract
Review

MeSH terms

Adult
Congenital Abnormalities / genetics
Female
Fingers / abnormalities*
Heart Defects, Congenital / genetics*
Humans
Syndrome