Abstract
Studies relating to the nature of the antigen-specific T-cell receptor are reviewed in the light of present knowledge of phylogenetic and ontogenetic development. It is suggested that this evidence supports the concept that immunoglobulin (Ig) is the T-cell receptor, and that the following conclusions may be tentatively drawn.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Aging
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Amphibians
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Animals
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B-Lymphocytes / immunology
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Binding Sites, Antibody
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Biological Evolution*
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Chickens
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Embryology*
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Fishes
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Humans
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Mice
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Phylogeny*
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Receptors, Antigen, B-Cell / analysis
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Spleen / cytology
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T-Lymphocytes / immunology*
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Thymus Gland / cytology
Substances
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Receptors, Antigen, B-Cell