[Danazol in the treatment of endometriosis]

Ter Arkh. 1994;66(10):55-7.
[Article in Russian]

Abstract

48 females with uterine endometriosis stage 1 and 2, 26 female with mild and moderate external endometriosis and 9 females with external in combination with internal endometriosis with the disease duration from 6 months to 10 years were given danazol in doses 200-400 mg/day for 6 months. The effect of the treatment proved to be very high: 37 patients were cured, 14 improved, 3 got pregnant. 11 patients needed the second treatment course. Side effects were rare. Depressed hyperactive menstrual cycle normalized quickly. It is inferred that danazol doses 200-400 mg/day are adequate for induction of complete or partial responses in internal and external endometriosis.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Chronic Disease
  • Danazol / adverse effects
  • Danazol / therapeutic use*
  • Drug Evaluation
  • Endometriosis / diagnosis
  • Endometriosis / drug therapy*
  • Female
  • Humans
  • Hysteroscopy
  • Middle Aged
  • Ultrasonography
  • Uterine Diseases / diagnosis
  • Uterine Diseases / drug therapy*
  • Uterus / diagnostic imaging

Substances

  • Danazol