Vesicular pemphigoid

Arch Dermatol. 1976 Oct;112(10):1402-4.

Abstract

Seven patients had a chronic eruption of small vesicles that was initially considered to be atypical dermatitis herpetiformis. Histopathologic studies disclosed a subepidermal bulla that was compatible with either bullous pemphigoid or dermatitis herpetiformis. Immunofluorescence studies demonstrated deposition of IgG or C3, Or both, at the basement-membrane zone (BMZ) in six of seven patients. In four patients, circulating BMZ antibodies were detected also. We belive that these cases represent a vesicular form of bullous pemphigoid.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Antibodies / analysis
  • Biopsy
  • Complement C3 / analysis
  • Dermatitis Herpetiformis / diagnosis*
  • Diagnosis, Differential
  • Female
  • Fluorescent Antibody Technique
  • Humans
  • Immunoglobulin G / analysis
  • Male
  • Skin Diseases, Vesiculobullous / diagnosis*
  • Skin Diseases, Vesiculobullous / immunology

Substances

  • Antibodies
  • Complement C3
  • Immunoglobulin G