The responses to sorption treatment have been analysed for 373 patients suffering from staphylococcal, allergic, purulent, polypous-purulent rhinosinusitis. For enterosorption a coal spherical phi EH sorbent was used. Application sorption was performed with fabric sorbent AYT-M2, nonfabric sorbent AHM-pi, dust phi EH sorbent. Gelevin was tried for tampon-free postoperative management after dissection of the paranasal sinuses. Sorbents application advances the efficacy of nasal and paranasal disease treatment.