Ah receptor: a novel ligand-activated transcription factor

Exp Clin Immunogenet. 1994;11(2-3):65-74. doi: 10.1159/000424195.

Abstract

Two years have passed since the Ah receptor (AhR) and the AhR nuclear translocator (Arnt) were revealed to constitute a novel ligand-activated transcription factor by molecular biological studies on cloned cDNAs. Many interesting properties of the AhR/Arnt system have begun to be elucidated. We present here a brief summary of the molecular biology of AhR and Arnt.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Aryl Hydrocarbon Receptor Nuclear Translocator
  • DNA-Binding Proteins*
  • Humans
  • Molecular Sequence Data
  • Receptors, Aryl Hydrocarbon / genetics
  • Receptors, Aryl Hydrocarbon / physiology*
  • Sequence Homology, Amino Acid
  • Signal Transduction / physiology
  • Transcription Factors / physiology*

Substances

  • ARNT protein, human
  • DNA-Binding Proteins
  • Receptors, Aryl Hydrocarbon
  • Transcription Factors
  • Aryl Hydrocarbon Receptor Nuclear Translocator