Contact allergy to 2-hydroxy-5-tert-butyl benzylalcohol and 2,6-bis(hydroxymethyl)-4-tert-butylphenol, components of a phenolic resin used in marking pens

Contact Dermatitis. 1994 Sep;31(3):154-6. doi: 10.1111/j.1600-0536.1994.tb01955.x.

Abstract

2-hydroxy-5-tert-butyl benzylalcohol and 2,6-bis(hydroxymethyl)-4-tert-butylphenol were identified as contact allergens in a phenolic resin used as a tackifier in the ink of a marking pen, which, after being used directly on the skin, caused an acute contact dermatitis on the hand of a 13-year-old boy. The patient also reacted to 4-tert-butylphenol-formaldehyde resin (BPF resin) 1% pet. included in the European standard series.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adolescent
  • Allergens
  • Butylated Hydroxytoluene / adverse effects
  • Butylated Hydroxytoluene / analogs & derivatives*
  • Butylated Hydroxytoluene / metabolism
  • Dermatitis, Allergic Contact / etiology*
  • Hand Dermatoses / etiology*
  • Humans
  • Ink*
  • Male

Substances

  • Allergens
  • Butylated Hydroxytoluene
  • 2,6-bis(hydroxymethyl)-4-tert-butylphenol
  • 2-hydroxy-5-tert-butylbenzyl alcohol