Molecular characterization of the porcine MHC class I region

Anim Genet. 1994 Oct;25(5):357-9. doi: 10.1111/j.1365-2052.1994.tb00373.x.

Abstract

A porcine cosmid library was screened with a human MHC class I cDNA. Four positive clones were isolated and mapped with different restriction endonucleases. Altogether nine SLA class I genes were identified and their positions located within restriction maps. Sizes of class I homologous DNA sequences varied between 3600 and 5800 bp. The distances between these regions ranged from 11,900 to 22,200 bp.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cloning, Molecular
  • Cosmids
  • DNA Restriction Enzymes
  • DNA, Complementary
  • Gene Library
  • Genes, MHC Class I*
  • Liver / immunology
  • Restriction Mapping
  • Swine / genetics*
  • Swine / immunology

Substances

  • DNA, Complementary
  • DNA Restriction Enzymes