Abstract
We found an epidemiological association of Hafnia alvei with diarrhea, because the organism was isolated from 12 of 77 (16%) adult Finnish tourists to Morocco who developed diarrhea and from 0 of 321 tourists without diarrhea (P < 0.001). From another group of 112 adult Finnish diarrheal patients, only 2 (2%) yielded H. alvei. In contrast to some Bangladeshi strains of H. alvei, the Finnish strains were negative for the attachment-effacement lesion by an in vitro fluorescent acting staining test and also did not show homology to the Escherichia coli attachment-effacement gene (eaeA) by PCR. These results suggest that a mechanism or mechanisms other than the attachment-effacement lesion may also be involved in the association of H. alvei with diarrhea.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Actins / analysis
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Adhesins, Bacterial*
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Adult
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Bacterial Adhesion
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Bacterial Outer Membrane Proteins / genetics
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Bacterial Proteins / analysis
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Bacterial Proteins / genetics
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Bangladesh
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Base Sequence
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Carrier Proteins*
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Diarrhea / epidemiology
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Diarrhea / microbiology*
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Enterobacteriaceae / genetics
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Enterobacteriaceae / isolation & purification*
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Enterobacteriaceae / pathogenicity
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Enterobacteriaceae Infections / epidemiology
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Enterobacteriaceae Infections / microbiology*
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Escherichia coli / genetics
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Escherichia coli Proteins*
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Feces / microbiology*
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Finland / epidemiology
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Humans
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Molecular Sequence Data
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Morocco
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Polymerase Chain Reaction
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Sequence Homology, Nucleic Acid
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Travel
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Virulence / genetics
Substances
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Actins
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Adhesins, Bacterial
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Bacterial Outer Membrane Proteins
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Bacterial Proteins
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Carrier Proteins
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Escherichia coli Proteins
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eaeA protein, E coli
Associated data
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GENBANK/Z47359
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GENBANK/Z47360