Antitumor and cardiotonic activity of imidazo[2,1-b]thiazole guanylhydrazones

In Vivo. 1994 Nov-Dec;8(6):1031-2.

Abstract

A number of imidazo[2,1-b]thiazole guanylhydrazones, whose antitumor activity has already been described, were tested as potential cardiotonic agents. The guanylhydrazone of 2,3-dihydro-6-chloroimidazo[2,1-b]thiazole-5-carboxaldehyde (2a) was the most interesting compound showing both antitumor and cardiotonic activity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology*
  • Cardiotonic Agents / pharmacology*
  • Guinea Pigs
  • Hydrazones / pharmacology
  • Imidazoles / pharmacology
  • In Vitro Techniques
  • Molecular Structure

Substances

  • Antineoplastic Agents
  • Cardiotonic Agents
  • Hydrazones
  • Imidazoles