Prolonged generalized pruritus associated with selective elevation of IgA as the presenting symptoms of sarcoidosis

Ann Allergy Asthma Immunol. 1995 May;74(5):387-9.

Abstract

Objective: The purpose of this case report is to describe the possible initial presentation of sarcoidosis as generalized prolonged pruritus.

Methods: In a patient presenting with prolonged generalized pruritus who also had selective elevation of IgA, the diagnosis of sarcoidosis was confirmed by bilateral interstitial infiltrates on chest radiograph, elevated angiotensin-converting enzyme, and dermal granuloma on skin biopsy from a recent rash.

Conclusion: Sarcoidosis should be added to the list of diseases associated with prolonged pruritus and routine chest radiographs should be obtained in these patients.

Publication types

  • Case Reports

MeSH terms

  • Granuloma / complications
  • Granuloma / diagnosis
  • Humans
  • Immunoglobulin A / blood*
  • Male
  • Middle Aged
  • Peptidyl-Dipeptidase A / blood
  • Pruritus / etiology*
  • Pruritus / immunology
  • Sarcoidosis / complications
  • Sarcoidosis / diagnosis*
  • Skin Diseases / complications
  • Skin Diseases / diagnosis*

Substances

  • Immunoglobulin A
  • Peptidyl-Dipeptidase A