PCS: an IBM-compatible microcomputer program for the analysis and display of voltage-clamp data

Comput Methods Programs Biomed. 1993 Jul;40(3):175-80. doi: 10.1016/0169-2607(93)90055-p.

Abstract

A program for IBM-compatible microcomputers is described which facilitates the analysis and manipulation of voltage-clamp data. PCS accepts pCLAMP acquired data as well as data from a more generalized binary data file. This cursor-driven program permits four modes of analysis: peak detection, averaging, integration and curve fitting, with direct graphical feedback of the results. Graphs of analysis results, such as current versus voltage relations (I-V curves), with tabulated data can be concisely printed using a HP Laserjet III. Selected current traces may also be plotted using the HP Laserjet III or exported to an ASCII comma and quotation mark delimited file suitable for import to a spreadsheet program.

MeSH terms

  • Animals
  • Barium / physiology
  • Calcium Channels / physiology
  • Computer Graphics*
  • Electrophysiology*
  • Evaluation Studies as Topic
  • Guinea Pigs
  • Ion Channels
  • Microcomputers*
  • Sarcolemma / physiology
  • Signal Processing, Computer-Assisted*
  • Software*
  • Ventricular Function

Substances

  • Calcium Channels
  • Ion Channels
  • Barium