Voltage-clamp and single channel analysis of Pb(2+)-induced current in isolated snail neurons

J Gyóri; O N Osipenko; T Kiss

Voltage-clamp and single channel analysis of Pb(2+)-induced current in isolated snail neurons

Acta Biol Hung. 1993;44(1):3-7.

Authors

J Gyóri¹, O N Osipenko, T Kiss

Affiliation

¹ Balaton Limnological Research Institute, Hungarian Academy of Sciences, Tihany.

PMID: 7684172

Abstract

Pb-activated outward current was investigated in intracellularly perfused, isolated snail neurons. Pb-ions induced non-inactivating but reversible current (IPb). The IPb showed concentration dependence. The I-V curve was linear with negative slope and the IPb proved to be Na-dependent.

MeSH terms

Animals
Evoked Potentials / drug effects
Helix, Snails
In Vitro Techniques
Ion Channels / drug effects
Ion Channels / physiology*
Lead / pharmacology*
Membrane Potentials
Neurons / drug effects
Neurons / physiology*

Substances

Ion Channels
Lead