Probable presence of beta(1-2)-linked oligomannosides that act as human immunoglobulin G3 epitopes and are distributed over a Candida albicans 14- to 18-kilodalton antigen

D Poulain; C Faille; C Delaunoy; P M Jacquinot; P A Trinel; D Camus

doi:10.1128/iai.61.3.1164-1166.1993

Probable presence of beta(1-2)-linked oligomannosides that act as human immunoglobulin G3 epitopes and are distributed over a Candida albicans 14- to 18-kilodalton antigen

Infect Immun. 1993 Mar;61(3):1164-6. doi: 10.1128/iai.61.3.1164-1166.1993.

Authors

D Poulain¹, C Faille, C Delaunoy, P M Jacquinot, P A Trinel, D Camus

Affiliation

¹ Unité INSERM 42, Villeneuve d'Ascq, France.

Abstract

Kinetic analysis of candidosis patients' immunoglobulin G3 response has shown that reactivity towards beta(1-2)-linked mannan-derived oligomannosides was associated with the recognition through metaperiodate-sensitive epitopes of a 14- to 18-kDa Candida albicans antigen unreactive with concanavalin A.

MeSH terms

Aged
Antigens, Fungal / chemistry*
Blotting, Western
Candida albicans / immunology*
Candidiasis / immunology*
Epitopes
Female
Fungal Proteins / chemistry
Fungal Proteins / immunology
Humans
Immunoglobulin G / immunology
Male
Mannosides / chemistry
Mannosides / immunology*
Middle Aged

Substances

Antigens, Fungal
Epitopes
Fungal Proteins
Immunoglobulin G
Mannosides