Assessment of structurally related chemicals: toxicity and ecotoxicity of acrylic acid and acrylic acid alkyl esters (acrylates), methacrylic acid and methacrylic acid alkyl esters (methacrylates)

Chemosphere. 1995 Jul;31(2):2637-59. doi: 10.1016/0045-6535(95)00136-v.

Abstract

BUA compiled the available data on toxicity and ecotoxicity for several acrylic and methacrylic acid esters and their corresponding acids. A comparison of these data revealed a qualitative similarity in the toxicological and ecotoxicological properties of the compounds considered. The data indicate that methacrylates are less reactive than the corresponding acrylates.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Acrylates / chemistry
  • Acrylates / metabolism
  • Acrylates / toxicity*
  • Animals
  • Bacteria / drug effects
  • Biodegradation, Environmental
  • Carcinogens / toxicity
  • Daphnia / drug effects
  • Eukaryota / drug effects
  • Fishes
  • Humans
  • Lethal Dose 50
  • Methacrylates / chemistry
  • Methacrylates / metabolism
  • Methacrylates / toxicity*
  • Rats
  • Skin / drug effects
  • Structure-Activity Relationship

Substances

  • Acrylates
  • Carcinogens
  • Methacrylates
  • methacrylic acid
  • acrylic acid