Structural and functional organization of the nuclear envelope

Curr Opin Cell Biol. 1995 Jun;7(3):301-9. doi: 10.1016/0955-0674(95)80083-2.

Abstract

The double-membrane nuclear envelope is punctuated by pores where the two membranes are joined. These pores are stabilized by the elaborate nuclear pore complex, which is anchored to the inner membrane by the nuclear lamina, as well as to other nuclear and cytoskeletal structures. Recent experiments have identified proteins involved in the stability of this organization as well as in the function of the nuclear pore complex, which we relate here to newer aspects of nuclear envelope structure.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Biological Transport, Active
  • Female
  • Membrane Proteins / physiology
  • Microscopy, Electron
  • Microscopy, Electron, Scanning
  • Nuclear Envelope / physiology*
  • Nuclear Envelope / ultrastructure*
  • Nuclear Proteins / physiology
  • Oocytes / physiology
  • Oocytes / ultrastructure
  • Xenopus

Substances

  • Membrane Proteins
  • Nuclear Proteins