Early sensitization to airborne allergens

Int Arch Allergy Immunol. 1995 Aug;107(4):595-8. doi: 10.1159/000237106.

Abstract

We report the case of a 7-month-old child with failure to thrive. Celiac disease was suspected because of highly raised antigliadin IgA and IgG antibodies and subtotal villous atrophy. In peripheral blood mononuclear-cells cellular proliferation was found in response to birch pollen, rye pollen and hazelnut extract. Born in June 1992 the infant had not yet experienced a birch pollen season. He had been fed with birch pollen allergy-associated carrot, apple and potato beginning at 6 weeks of life. In the serum, specific IgG, IgM and IgA to birch pollen and profilin, rye pollen and hazelnut antigens were detectable, indicating possible in utero sensitization or T cell cross-reactivity due to early sensitization with related food antigens.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Allergens / immunology*
  • Food Hypersensitivity / etiology*
  • Humans
  • Infant
  • Lymphocyte Activation
  • Male
  • Pollen / immunology*
  • T-Lymphocytes / immunology

Substances

  • Allergens