Renal masses: assessment of corticomedullary-phase and nephrographic-phase CT scans

Radiology. 1995 Aug;196(2):445-51. doi: 10.1148/radiology.196.2.7617859.

Abstract

Purpose: To evaluate the role of thin-section helical computed tomography (CT) performed during the corticomedullary phase (CMP) and nephrographic phase (NP) of contrast enhancement in the detection and characterization of renal masses.

Materials and methods: Renal CT scans and medical records of 33 patients were retrospectively reviewed. In all examinations, 5-mm-thick, contiguous, helical-mode scans were obtained before and 40 seconds after initiation of dynamic bolus injection of contrast material (CMP images); 5-mm-thick, contiguous, axial-mode scans were obtained after completion of CMP scanning (NP images).

Results: At review of CMP, NP, and combination images, 259, 389, and 417 lesions, respectively, were identified. The greatest difference in detection occurred in the renal medulla, with 25 lesions identified on CMP images and 111 lesions identified on NP images. False-positive results occurred when CMP images were reviewed without NP images.

Conclusion: CT scans obtained only during the CMP of contrast enhancement fail to depict many renal masses that are easily seen on NP images.

Publication types

  • Comparative Study

MeSH terms

  • False Positive Reactions
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Iohexol
  • Kidney Cortex / diagnostic imaging
  • Kidney Diseases / diagnostic imaging*
  • Kidney Diseases / epidemiology
  • Kidney Medulla / diagnostic imaging
  • Kidney Neoplasms / diagnostic imaging*
  • Kidney Neoplasms / epidemiology
  • Male
  • Middle Aged
  • Retrospective Studies
  • Sensitivity and Specificity
  • Time Factors
  • Tomography, X-Ray Computed / methods*

Substances

  • Iohexol