Primary systemic amyloidosis presenting with polyneuropathy characterized by very long survival

Acta Neurol Scand. 1995 Jun;91(6):511-3. doi: 10.1111/j.1600-0404.1995.tb00455.x.

Abstract

We report a case of primary systemic amyloidosis associated with IgA monoclonal gammopathy presenting with sensorimotor polyneuropathy. For 10 years the neurological symptoms were the only clinical manifestation. A great deal of therapy was given right from the onset of symptoms and the very long survival of the patient may have been due to these efforts.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amyloid Neuropathies / diagnosis*
  • Amyloidosis / diagnosis*
  • Amyloidosis / drug therapy
  • Amyloidosis / therapy
  • Combined Modality Therapy
  • Cyclophosphamide / administration & dosage
  • Cyclophosphamide / therapeutic use
  • Electromyography
  • Humans
  • Immunoelectrophoresis
  • Immunoglobulin A / blood*
  • Immunosuppressive Agents / administration & dosage
  • Immunosuppressive Agents / therapeutic use
  • Male
  • Median Nerve
  • Neural Conduction
  • Plasma Exchange
  • Sural Nerve / ultrastructure
  • Survival*

Substances

  • Immunoglobulin A
  • Immunosuppressive Agents
  • Cyclophosphamide