Pancreatic carcinoma is one of the most aggressive visceral malignancies with lethal ending in 99% of cases. Although diagnostic methods make a great progress, the world epidemiologists consider this disease to be increasing. The main reason for this is probably the problem of making early diagnosis. Various diagnostic techniques including ultrasonography often make no difference between benign and malignant changes. The aim of this paper is to consider values of pancreatic functions under the control of ultrasound in a group of patients. The examination included patients with evident pancreatic changes. By cytopathologic analysis of the gathered material clear diagnosis was made. In most cases malignancy was established. The aim of diagnostic examination is to make diagnosis as early as possible, using minimal number of tests which should be the least invasive and traumatic for patients. As a diagnostic method ultrasonography is fast and simple which provides better chances for patients with pancreatic carcinoma.