Abstract
An overview of calculations of isotope effects on biochemical and chemical reactions using quantum chemistry methods is presented . Usefulness of different levels of theoretical scrutiny for such calculations is critically discussed.
Publication types
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, P.H.S.
-
Review
MeSH terms
-
Chemical Phenomena
-
Chemistry, Physical
-
Decarboxylation
-
Isotopes*
-
Isoxazoles / metabolism
-
Kinetics
-
Methyltransferases
-
Models, Chemical
-
Molecular Structure
-
Nitriles / metabolism
-
Protein Binding
Substances
-
Isotopes
-
Isoxazoles
-
Nitriles
-
methylisonitrile
-
Methyltransferases