Transcriptional control of dacB, which encodes a major sporulation-specific penicillin-binding protein

J Bacteriol. 1994 Dec;176(24):7767-9. doi: 10.1128/jb.176.24.7767-7769.1994.

Abstract

Sporulation-specific sigma factor E (sigma E) of Bacillus subtilis is both necessary and sufficient for transcription of the dacB gene, which encodes penicillin-binding protein 5*. Evidence in support of this conclusion was obtained by primer extension analysis of dacB transcripts and the induction of active sigma E with subsequent synthesis of PBP 5* in vegetative cells.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Bacillus subtilis / genetics*
  • Bacillus subtilis / growth & development
  • Bacterial Proteins / metabolism
  • Base Sequence
  • Carrier Proteins / biosynthesis
  • Carrier Proteins / genetics*
  • Gene Expression Regulation, Bacterial*
  • Hexosyltransferases*
  • Molecular Sequence Data
  • Muramoylpentapeptide Carboxypeptidase / biosynthesis
  • Muramoylpentapeptide Carboxypeptidase / genetics*
  • Penicillin-Binding Proteins
  • Penicillins / metabolism
  • Peptidyl Transferases*
  • RNA, Bacterial / genetics
  • Recombinant Fusion Proteins / biosynthesis
  • Sigma Factor*
  • Spores, Bacterial / genetics*
  • Spores, Bacterial / growth & development
  • Transcription Factors*
  • Transcription, Genetic*

Substances

  • Bacterial Proteins
  • Carrier Proteins
  • Penicillin-Binding Proteins
  • Penicillins
  • RNA, Bacterial
  • Recombinant Fusion Proteins
  • Sigma Factor
  • Transcription Factors
  • sporulation-specific sigma factors
  • Peptidyl Transferases
  • Hexosyltransferases
  • Muramoylpentapeptide Carboxypeptidase