Anatomical data supporting the concept of prefrontal influences upon hypothalamo-medullary relays in the rat

Neurosci Lett. 1994 Mar 14;169(1-2):17-20. doi: 10.1016/0304-3940(94)90346-8.

Abstract

Based upon physiological evidence, it has been suggested that the lateral prefrontal cortex (LPFC) influences cardiovascular functions by acting upon hypothalamic relays to the rostral ventrolateral medulla (RVLM). Presented in this paper is preliminary anatomical evidence to support such an hypothesis. Using a combination of tracers, it was observed that within the posterolateral hypothalamus there was an overlap of input from the LPFC and output to the RVLM.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Autoradiography
  • Axons / physiology
  • Histocytochemistry
  • Horseradish Peroxidase
  • Hypothalamus / anatomy & histology*
  • Hypothalamus / cytology
  • Hypothalamus / physiology
  • Medulla Oblongata / anatomy & histology*
  • Medulla Oblongata / cytology
  • Medulla Oblongata / physiology
  • Microscopy, Fluorescence
  • Neural Pathways / anatomy & histology
  • Neural Pathways / cytology
  • Neural Pathways / physiology
  • Neurons / physiology
  • Prefrontal Cortex / anatomy & histology*
  • Prefrontal Cortex / cytology
  • Prefrontal Cortex / physiology
  • Rats
  • Rats, Sprague-Dawley
  • Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate
  • Wheat Germ Agglutinins

Substances

  • Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate
  • Wheat Germ Agglutinins
  • Horseradish Peroxidase