Abstract
The human CD36 is a member of a gene family of structurally related glycoproteins and functions as a receptor for collagen type I and thrombospondin. CD36 also binds to red blood cells infected with the human malaria parasite Plasmodium falciparum. In the present study, the CD36 gene was assigned to chromosome 7 by using the polymerase chain reaction with DNA from human-hamster somatic cell hybrids. Furthermore, the use of a CD36 genomic probe has allowed the localization of the CD36 locus to the 7q11.2 band by fluorescence in situ hybridization coupled with GTG-banding.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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CD36 Antigens
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Chromosome Mapping
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Chromosomes, Human, Pair 7*
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Collagen / metabolism
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Cricetinae
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DNA / genetics
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Humans
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Hybrid Cells
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In Situ Hybridization, Fluorescence
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Integrins / genetics*
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Membrane Glycoproteins / metabolism
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Molecular Sequence Data
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Platelet Membrane Glycoproteins / genetics*
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Polymerase Chain Reaction
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Receptors, Collagen
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Receptors, Cytoadhesin / genetics*
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Receptors, Immunologic*
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Receptors, Lipoprotein*
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Receptors, Scavenger
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Thrombospondins
Substances
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CD36 Antigens
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Integrins
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Membrane Glycoproteins
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Platelet Membrane Glycoproteins
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Receptors, Collagen
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Receptors, Cytoadhesin
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Receptors, Immunologic
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Receptors, Lipoprotein
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Receptors, Scavenger
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Thrombospondins
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Collagen
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DNA