Abstract
Buprenorphin was given to 12 patients as a postoperative analgesic after neurosurgery, and the effects of the drug on the circulation, respiration and the electroencephalogram were studied. The circulation was not significantly affected, respiration was moderately depressed, the analgesic action was satisfactory. The depression of consciousness was reflected in the electroencephalographic pattern.
MeSH terms
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Adolescent
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Adult
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Blood Gas Analysis
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Blood Pressure / drug effects
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Brain / drug effects*
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Brain Diseases / surgery
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Buprenorphine / adverse effects
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Buprenorphine / pharmacology*
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Cardiac Output / drug effects
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Cardiovascular System / drug effects*
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Child
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Electroencephalography
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Female
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Heart Rate / drug effects
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Humans
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Middle Aged
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Morphinans / pharmacology*
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Postoperative Care*
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Respiration / drug effects*