Abstract
Cycloheximide caused no changes in activation of arginase and ornitine-sigma-ketoglutarate transaminase during loads, but the activation of ornitine decarboxylase and putrescine and polyamines production was sharply reduced. Physical load caused a significantly lower activation of enzymes of ornitine metabolism and a smaller production of polyamines in muscles of trained animals. The extent of polyamines synthesis is positively correlated with the magnitude of muscles work hypertrophy.
Publication types
-
Comparative Study
-
English Abstract
MeSH terms
-
Animals
-
Arginase / metabolism
-
Arginine / analysis
-
Cycloheximide / pharmacology
-
Muscles / analysis
-
Muscles / metabolism*
-
Ornithine Decarboxylase / metabolism
-
Ornithine-Oxo-Acid Transaminase / metabolism
-
Physical Exertion*
-
Polyamines / biosynthesis*
-
Putrescine / analysis
-
Rats
-
Spermidine / analysis
-
Spermine / analysis
Substances
-
Polyamines
-
Spermine
-
Arginine
-
Cycloheximide
-
Ornithine-Oxo-Acid Transaminase
-
Arginase
-
Ornithine Decarboxylase
-
Spermidine
-
Putrescine