Effects of oral contraceptives on zinc and copper levels in human plasma and endometrium during the menstrual cycle

Arch Gynecol. 1978 Dec 29;226(4):303-6. doi: 10.1007/BF02119220.

Abstract

Effects of Ovulen-21, Demulen, Enovid-E and Ovral on zinc and copper levels in human plasma and endometrium during the menstrual cycle have been studied. Both plasma and endometrium copper levels were significantly elevated above the control values (P less than 0.001) in women taking oral contraceptives while the zinc levels remained reasonable constant.

MeSH terms

  • Adult
  • Contraceptives, Oral / pharmacology*
  • Copper / analysis
  • Copper / blood*
  • Endometrium / analysis
  • Endometrium / drug effects*
  • Ethynodiol Diacetate / pharmacology
  • Female
  • Humans
  • Menstruation
  • Mestranol / pharmacology
  • Norethynodrel / pharmacology
  • Zinc / analysis
  • Zinc / blood*

Substances

  • Contraceptives, Oral
  • Ethynodiol Diacetate
  • Copper
  • Norethynodrel
  • Mestranol
  • Zinc