Steady state drug or fluid delivery to injured or transected spinal cord of rats

Lab Anim Sci. 1981 Dec;31(6):701-3.

Abstract

Fluids or drugs were delivered to injured or transected spinal cords of rats at a controlled rate and concentration. The technique used a catheter system molded to the shape of the spinal cord and attached to an osmotic minipump reservoir that was subcutaneously by the rats.

MeSH terms

  • Animals
  • Catheterization
  • Evans Blue
  • Male
  • Perfusion / instrumentation
  • Perfusion / methods*
  • Pharmaceutical Preparations / administration & dosage*
  • Postoperative Care
  • Prostheses and Implants
  • Rats
  • Spinal Cord / blood supply
  • Spinal Cord Injuries / therapy*

Substances

  • Pharmaceutical Preparations
  • Evans Blue