The treatment of severe Raynaud's phenomenon with verapamil

J Clin Pharmacol. 1982 Jan;22(1):74-6. doi: 10.1002/j.1552-4604.1982.tb05712.x.

Abstract

Verapamil was evaluated in 16 patients with severe Raynaud's phenomenon. Fifty per cent of patients experienced subjective improvement by history, but only one patient had a substantial reduction in the frequency of Raynaud's phenomenon as assessed by diary analysis. We conclude that verapamil is not effective in most patients with severe Raynaud's phenomenon.

Publication types

  • Clinical Trial

MeSH terms

  • Clinical Trials as Topic
  • Double-Blind Method
  • Hemodynamics
  • Humans
  • Raynaud Disease / drug therapy*
  • Raynaud Disease / physiopathology
  • Verapamil / adverse effects
  • Verapamil / therapeutic use*

Substances

  • Verapamil